Methadone 20 mg Hydrochloride – Precision Oral Tablet

Methadone 20 mg Hydrochloride tablets are a high-purity opioid medication, developed for both opioid dependence therapy and the management of severe pain. Manufactured according to advanced GMP standards, these tablets ensure reliable potency, predictable safety, and regulatory compliance for clinical and hospital use.

Product Summary

• Active Ingredient: Methadone hydrochloride, 20 mg per tablet
• Form: Oral tablet, white to off-white, hexagonal/uncoated; marked “M20” or similar identifier
• Packaging: Multiple blister pack and bottle options for institutional and pharmacy dispensing
• Regulatory Approval: Authorized in numerous global markets for opioid maintenance, withdrawal, and pain indications.

Indications and Usage of Methadone 20 mg

• Opioid Substitution Therapy:
  Indicated as maintenance treatment in opioid-dependent individuals where abstinence is not immediately achievable.
• Medically Supervised Detoxification:
  Supports gradual reduction of opioid dependence, minimizing withdrawal severity.
• Pain Management:
  Appropriate for moderate to severe chronic pain, especially when standard treatments are inadequate or contraindicated.

Dosage and Administration of Methadone 20 mg

• Initiation in Opioid-Dependent Adults:
  Start with 10 mg to 20 mg per day; titrate carefully based on withdrawal symptoms and tolerability, not exceeding recommended incremental increases.
• Opioid-Naive Patients (for pain):
  Lower initial doses are advised with slow upward adjustment.

Dosing should be specifically tailored and supervised by experienced medical professionals. Methadone’s long half-life calls for careful titration to avoid toxicity.

Key Features and Benefits of Methadone 20 mg

• Consistent dose accuracy for optimal patient safety
• Long-acting pharmacokinetics enable once-daily dosing for maintenance therapy
• Proven efficacy in suppressing withdrawal and cravings in opioid substitution
• Effective for neuropathic and cancer-related pain with stable release

Quality & Compliance

• Manufacturer certified under cGMP and ISO standards
• Tablets tested for identity, strength, dissolution, and purity
• Compliance with regional and international pharmacopeias (USP/BP/EP)

Safety Information

Contraindications:

• Known hypersensitivity to methadone or hydrochloride salts
• Severe respiratory depression, acute asthma, or compromised airway
• Active CNS depression or coma

Warnings:

• Monitor patients closely for respiratory depression and QT interval prolongation
• Avoid abrupt cessation; dose reductions must be gradual.
• Use with caution in patients with cardiac arrhythmias, hepatic or renal impairment, and in elderly or frail patients

Common Adverse Effects:
Sweating, constipation, lightheadedness, drowsiness, nausea, and, less commonly, cardiac or respiratory complications.

Drug Interactions:
Potential interactions with CNS depressants, serotonergic agents, CYP450 inducers/inhibitors, and some antivirals or antibiotics. Concomitant use may elevate risks of sedation, serotonin syndrome, or impaired clearance.

Why Choose Methadone 20 mg Hydrochloride?

• Pharmaceutical-grade consistency for clinical and addiction-treatment settings
• Versatile oral formulation for tailored therapy
• Secure, traceable supply chain for institutional purchasing
• Backed by full technical dossiers and regulatory documentation

For comprehensive product specifications, quality certificates, or bulk ordering inquiries, please contact our specialist team.

Use by or under the direction of qualified healthcare professionals only. Methadone therapy should be initiated and supervised by practitioners experienced in opioid management.