Fampridine 10 mg ER – GMP Certified for MS Patients

Product Overview

Fampridine 10 mg that belongs to CNS group medicines is an oral modified-release tablet designed to improve walking ability in adult patients with multiple sclerosis (MS) who are experiencing walking difficulties. Specifically, by enhancing nerve signal conduction, fampridine provides meaningful improvements in muscle function and patient mobility, therefore contributing to a better quality of life.

Vonage Pharma manufactures fampridine 10 mg tablets under stringent GMP conditions, ensuring high purity, efficacy, and safety for healthcare providers and patients alike.

Mechanism of Action

Fampridine acts as a selective potassium channel blocker. In patients with MS, nerve damage disrupts signal transmission; Fampridine prolongs the action potential by blocking potassium channels on demyelinated nerve fibers. As a result, this action improves nerve conduction and muscle response, thereby ultimately enhancing walking speed and coordination.

Indications and Uses of Fampridine 10 mg

• Improvement of walking ability in adult MS patients with walking disability

• Adjunctive treatment to help patients regain functional mobility

• Suitable for long-term use under physician supervision

Clinical trials have demonstrated that fampridine 10 mg significantly improves walking speed and endurance, with a responder rate of approximately 35-40%, compared to placebo.

Dosage and Administration

• Recommended dose: 10 mg orally twice daily, approximately 12 hours apart

• Tablets should be swallowed whole with water, not crushed or chewed

• Dose adjustments are typically not necessary; however, dose reduction is advised in renal impairment

Safety Profile and Side Effects

Fampridine 10 mg is generally well tolerated. Common side effects include:

• Insomnia

• Dizziness

• Headache

• Urinary tract infections

Seizures are a rare but serious adverse event, especially in patients with a history of seizures or renal impairment. Hence, screening and ongoing monitoring are essential.

Precautions and Contraindications

• Not recommended in patients with a history of seizures

• Use with caution in patients with moderate to severe renal impairment

• Contraindicated in hypersensitivity to fampridine or any excipients

Packaging and Storage

• Modified-release tablets, 10 mg strength

• Packaging: blister packs containing 14 or 28 tablets

• Store below 25°C in a dry place, protected from light

Why Choose Vonage Pharma’s Fampridine 10 mg?

Vonage Pharma provides high-quality fampridine 10 mg tablets manufactured under strict GMP protocols. Furthermore, we ensure consistent reliability and potency, while also supporting pharmaceutical providers with expert service and timely supply.