Bosentan Monohydrate 62.5mg

Bosentan 62.5mg, manufactured by PluviaEndo, is an FDA-approved Respiratory medication designed to treat pulmonary arterial hypertension (PAH). This potent endothelin receptor antagonist helps improve exercise capacity and overall quality of life for patients suffering from this serious condition. Additionally, Bosentan is effective in reducing the occurrence of digital ulcers in patients with systemic sclerosis.

Key Features

• Generic Name: Bosentan (as Monohydrate)
• Strength: 62.5 mg
• Formulation: Film-coated tablet
• Manufacturer: PluviaEndo
• Prescription Status: Prescription Required

How Does Bosentan 62.5mg Work?

Bosentan works by blocking the action of endothelin, a substance in the body that causes blood vessels to constrict. By inhibiting both Endothelin-A (ETA) and Endothelin-B (ETB) receptors, Bosentan promotes vasodilation, which leads to:

• Reduced pulmonary vascular resistance
• Improved blood flow in the lungs
• Enhanced exercise tolerance for patients with PAH

Indications of Bosentan 62.5mg

This medicine is indicated for:

1. Pulmonary Arterial Hypertension (PAH): To improve exercise capacity and delay clinical worsening.
2. Systemic Sclerosis: To reduce the number of new digital ulcers in patients with systemic sclerosis and ongoing digital ulcer disease.

Dosage and Administration

Recommended Dosage

• Initial Dose: 62.5 mg taken orally twice daily for the first 4 weeks.
• Maintenance Dose: After 4 weeks, the dose may be increased to 125 mg taken twice daily based on patient tolerance and response.

Administration Guidelines

• Take Bosentan with or without food.
• Ensure consistent timing for morning and evening doses.

Monitoring Requirements

Regular monitoring is crucial during treatment:

• Liver Function Tests: Monthly during the first six months, then quarterly.
• Hemoglobin Levels: Regular checks to monitor for anemia.

Safety Information of Bosentan 62.5mg

Common Side Effects

Patients may experience:

• Headache
• Fluid retention
• Liver enzyme elevation
• Anemia

Serious Side Effects of Bosentan 62.5mg

Less common but serious effects include:

• Hepatotoxicity (liver damage)
• Significant drops in hemoglobin levels
• Allergic reactions

Contraindications

Bosentan should not be used in:

• Pregnant women due to potential risks to the fetus.
• Individuals with severe hepatic impairment.
• Patients taking cyclosporine A.

Why Choose PluviaEndo’s Bosentan 62.5mg?

PluviaEndo is committed to producing high-quality pharmaceuticals that adhere to stringent global regulations and Good Manufacturing Practice (GMP) guidelines. By choosing Bosentan from PluviaEndo, healthcare providers can ensure that patients receive a reliable and effective treatment option for managing PAH.

Conclusion

Bosentan 62.5mg represents a significant advancement in the treatment of pulmonary arterial hypertension and systemic sclerosis-related digital ulcers. With its proven efficacy and safety profile, this medication from PluviaEndo can significantly improve your quality of life. Consult your healthcare provider today to see if Bosentan 62.5mg is right for you. For more information or to place an order, please contact your healthcare provider or visit our website. Always seek professional medical advice before starting any new medication regimen. Your health is paramount—make informed decisions with the guidance of your healthcare team!

Frequently Asked Questions