Methadone HCl 40 mg Tablets – GMP-Certified
Scored Methadone HCl 40 mg Tablets
Box (100 tablets)
Comprehensive Product Overview
Vonage Pharma‘s Methadone HCl 40 mg tablets represent a high-quality pharmaceutical solution for medication-assisted treatment (MAT) and chronic pain management in analgesics category. Manufactured in our GMP-certified facility, these immediate-release, scored tablets combine precise dosing accuracy with exceptional therapeutic performance.
As a Schedule II controlled substance, our Methadone HCl 40 mg formulation undergoes rigorous quality controls to ensure:
- Batch-to-batch consistency for reliable clinical outcomes
- Optimal bioavailability (>80% absorption)
- Extended duration of action (24-36 hour half-life)
- Flexible dosing options through scored tablets
Therapeutic Applications & Clinical Benefits of Methadone HCl 40
Our Methadone HCl 40 mg tablets are indicated for:
1. Opioid Use Disorder Treatment
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Reduces withdrawal symptoms by 89% in clinical studies
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Maintains patients in treatment programs 3x longer than non-medicated approaches
2. Chronic Pain Management
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Effective for cancer-related pain and palliative care
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Lower abuse potential compared to short-acting opioids
3. Hospital Detoxification Protocols
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Smooth transition from illicit opioids
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Gradual dose reduction capability
Technical Specifications & Quality Assurance
Core Product Attributes
| Parameter | Specification | Test Method |
|---|---|---|
| Dosage Form | Immediate-release, scored tablet | Visual |
| Appearance | White, round, film-coated | USP <621> |
| Dimensions | 8mm diameter | Vernier caliper |
| Dissolution | ≥85% in 30 min (pH 6.8) | USP <711> |
| Assay (HPLC) | 98.0-102.0% | USP <621> |
Stability & Packaging of Methadone HCl 40
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Shelf life: 24 months at 25°C/60% RH
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Primary packaging:
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Alu-Alu blisters (10/30/100 count) with UV protection
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HDPE bottles (100/500/1000 count) with tamper-evident seals
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Secondary packaging: Customizable carton labeling in multiple languages
Manufacturing & Regulatory Excellence
Production Capabilities
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Batch sizes: 100,000 to 5 million tablets
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Annual capacity: 50 million tablets
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Excipient standards: USP/EP grade, with lactose-free options
Compliance Documentation
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Active DMF/ASMF for US/EU markets
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Complete CTD modules available
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Batch-specific documentation:
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Certificate of Analysis
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Residual solvent reports
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Elemental impurity testing (ICH Q3D)
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Commercial Advantages for B2B Partners
Addiction Treatment Centers
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Bulk discounts: 15% savings on 500K+ units
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Custom packaging: Clinic-specific branding
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Regulatory support: MAT program compliance guidance
Pharmaceutical Distributors
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Private labeling services
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Tender documentation preparation
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GDP-compliant global logistics
Hospital Groups
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Emergency supply protocols
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Cold chain storage options
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Pharmacovigilance reporting support
Global Supply Chain Reliability of Methadone HCl 40
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Standard lead time: 6-8 weeks
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Express manufacturing: 4 weeks for urgent orders
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Shipping options:
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EXW/FCA terms available
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CITES-certified narcotics transport
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Ordering & Samples
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Minimum Order Quantity: 100,000 tablets
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Sample policy: 50 tablets for quality validation
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Payment terms: Negotiable LC/TT arrangements
Need MSDS or stability data? Our regulatory team provides comprehensive support. Contact US!
FAQ
What is Methadone Hydrochloride 40 mg?
Methadone Hydrochloride 40 mg is an opioid medication used for opioid dependence treatment and for managing chronic severe pain.
What is the main use of Methadone Hydrochloride 40 mg?
It is primarily used in opioid substitution therapy for patients with opioid dependence, as well as for the management of severe pain.
Which countries have the highest demand for Methadone Treatment?
ASEAN countries such as Vietnam, Indonesia, and the Philippines, along with several African and Middle Eastern countries, show the highest demand for methadone in addiction treatment programs.
How does Vonage Pharma supply Methadone Hydrochloride 40 mg?
We provide Methadone Hydrochloride 40 mg both as API (Active Pharmaceutical Ingredient) and as FDF (Finished Dosage Form) for pharmaceutical manufacturers and distributors worldwide.
Does Methadone Hydrochloride 40 mg require special licensing?
Yes, methadone is a controlled substance, and its importation and distribution require proper regulatory approvals and licenses in the target country.
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