Methadone HCl 40 mg Tablets – GMP-Certified

Comprehensive Product Overview

Vonage Pharma‘s Methadone HCl 40 mg tablets represent a high-quality pharmaceutical solution for medication-assisted treatment (MAT) and chronic pain management in analgesics category. Manufactured in our GMP-certified facility, these immediate-release, scored tablets combine precise dosing accuracy with exceptional therapeutic performance.

As a Schedule II controlled substance, our Methadone HCl 40 mg formulation undergoes rigorous quality controls to ensure:

1. Batch-to-batch consistency for reliable clinical outcomes
2. Optimal bioavailability (>80% absorption)
3. Extended duration of action (24-36 hour half-life)
4. Flexible dosing options through scored tablets

Therapeutic Applications & Clinical Benefits of Methadone HCl 40

Our Methadone HCl 40 mg tablets are indicated for:

1. Opioid Use Disorder Treatment

• Reduces withdrawal symptoms by 89% in clinical studies

• Maintains patients in treatment programs 3x longer than non-medicated approaches

2. Chronic Pain Management

• Effective for cancer-related pain and palliative care

• Lower abuse potential compared to short-acting opioids

3. Hospital Detoxification Protocols

• Smooth transition from illicit opioids

• Gradual dose reduction capability

Technical Specifications & Quality Assurance

Core Product Attributes

Stability & Packaging of Methadone HCl 40

• Shelf life: 24 months at 25°C/60% RH

• Primary packaging:

  • Alu-Alu blisters (10/30/100 count) with UV protection

  • HDPE bottles (100/500/1000 count) with tamper-evident seals

• Secondary packaging: Customizable carton labeling in multiple languages

Manufacturing & Regulatory Excellence

Production Capabilities

• Batch sizes: 100,000 to 5 million tablets

• Annual capacity: 50 million tablets

• Excipient standards: USP/EP grade, with lactose-free options

Compliance Documentation

• Active DMF/ASMF for US/EU markets

• Complete CTD modules available

• Batch-specific documentation:

  • Certificate of Analysis

  • Residual solvent reports

  • Elemental impurity testing (ICH Q3D)

Commercial Advantages for B2B Partners

Addiction Treatment Centers

• Bulk discounts: 15% savings on 500K+ units

• Custom packaging: Clinic-specific branding

• Regulatory support: MAT program compliance guidance

Pharmaceutical Distributors

• Private labeling services

• Tender documentation preparation

• GDP-compliant global logistics

Hospital Groups

• Emergency supply protocols

• Cold chain storage options

• Pharmacovigilance reporting support

Global Supply Chain Reliability of Methadone HCl 40

• Standard lead time: 6-8 weeks

• Express manufacturing: 4 weeks for urgent orders

• Shipping options:

  • EXW/FCA terms available

  • CITES-certified narcotics transport

Ordering & Samples

• Minimum Order Quantity: 100,000 tablets

• Sample policy: 50 tablets for quality validation

• Payment terms: Negotiable LC/TT arrangements

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