Methadone 25 mg/5 ml Oral Solution for Opioid Dependence and Pain Care

Methadone Hydrochloride Oral Solution (25 mg/5 ml) is a pharmaceutical-grade liquid formulation designed for accurate and flexible dosing in the treatment of opioid dependence and severe pain in analgesics category. This oral solution delivers a consistent 25 mg dose per 5 ml, supporting individualized therapy regimens in clinical, hospital, and community settings.

Product Overview

• Active Ingredient: Methadone hydrochloride, 25 mg per 5 ml of oral solution
• Formulation: Clear, pale yellow syrup with precise dosing capabilities
• Packaging: Supplied in secure bottles with child-resistant caps and calibrated dosing devices for exact measurement
• Compliance: Manufactured to meet USP, BP, and international quality standards adhering to GMP certification

Indications of Methadone 25 mg

Methadone 25 mg oral solution is indicated for:

• Maintenance therapy in opioid use disorder (OUD), as part of medication-assisted treatment protocols
• Medically supervised opioid detoxification and tapering schedules
• Management of moderate to severe chronic pain where alternative opioid formulations are unsuitable or impractical

Benefits and Features of Methadone 25 mg

• Flexible Dosing Precision: The oral liquid format allows fine-tuned dose adjustments tailored to patient needs, including those with difficulty swallowing tablets.
• Improved Absorption and Bioavailability: The solution form ensures rapid and consistent therapeutic effects.
• Enhanced Patient Compliance: Easy-to-administer syrup fosters better adherence in outpatient treatment and harm reduction programs.

Dosage and Administration

• Initiate and adjust methadone dosing carefully under medical supervision, considering patient opioid tolerance and clinical condition.
• Typical maintenance doses range from 20 mg to 30 mg per day, measured accurately using the supplied 5 ml dosing device.
• Monitor patients during titration for signs of toxicity or withdrawal, adjusting dosages accordingly.
• Administer orally; avoid substitution of measuring devices to maintain dose accuracy.

Safety Information about Methadone 25 mg

Contraindications

• Known allergy to methadone or any excipients in the formulation
• Severe respiratory impairment or acute bronchial asthma
• Paralytic ileus, coma, or significant CNS depression

Precautions

• Monitor cardiac function due to potential QT interval prolongation
• Avoid abrupt discontinuation; taper doses gradually
• Use caution in elderly, hepatic, or renal-compromised patients

Adverse Effects
Common side effects include sedation, dizziness, nausea, constipation, sweating, and rarely, serious cardiac arrhythmias.

Drug Interactions
Be cautious of enhanced sedation with concurrent CNS depressants and altered methadone metabolism by CYP450 enzyme modulators.

Quality and Regulatory Compliance

• Product manufactured following strict GMP guidelines
• Batch-tested for uniform potency, purity, and quality assurance
• Complete technical and regulatory documentation available to support healthcare providers

Why Choose Methadone 25 mg Oral Solution from Vonage Pharma?

• Accurate liquid dosing supports personalized treatment plans
• Suitable for patients requiring flexible dosing and alternative to tablets
• Reliable global supply with comprehensive professional support
• Fully aligned with opioid substitution therapy and harm reduction initiatives in Thailand and ASEAN markets

For more information on specifications, ordering, and clinical support, please contact Vonage Pharma’s expert team.

Intended for use by licensed healthcare professionals only. Methadone therapy requires careful initiation and monitoring by experienced clinicians.